questions :
Good afternoon Doctor,
My husband and I have been married for two years, but have not been blessed with offspring. Once checked, it turns out the levels of ASA (Anti Sperm) I was very high around 65,000. I ask, is there any other actions besides PLI or drugs that can overcome the problem of high ASA? thanks.
Answer:
Good afternoon Ny,
Currently the most effective treatment for high ASA therapy only PLI. PLI (Paternal Leukocyte Immunization) or also known as Leukocyte Immunization husband (ILS) is a therapy that is given to lower sperm antibodies in women who have excessive husband's sperm antibodies.
Excessive sperm antibodies makes it difficult for sperm to get to the egg, because it is always rejected and become dysfunctional, so it does not allow for fertilization and pregnancy.
Every woman who had never been exposed to sperm does have antibodies against the sperm of her husband, but in some women these antibodies overreact.
PLI therapy given by injecting white blood cells in husband under the skin wife under the skin wife.It aims to reduce wife sperm antibodies that can be tolerated by the body and allow for fertilization.
Therapy at least 3 times the distance of 3 weeks. Serum containing white blood cells, the husband will be injected under the skin at the wife. After treatment, patients are advised to perform reassessment imunoandrologi test
When the results have reached normal limits it is not necessary to resume therapy. If not, repeat do therapy until it reaches the normal limit
Before any therapy PLI, there are two ways that are usually done to pair with excessive sperm antibodies could be pregnant, that is with the use of condoms and drug imunosupressor.
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By using a condom means sperm antibodies let down by itself, by limiting exposure to sperm. But this way should take a long time, about 6 to 1 year. Not to mention if you frequently eat foods that contain protein allergens.
This would make the antibodies more long period of decline. Another way to use the drug imunosupressor.
Unfortunately, using this drug all the antibodies in the body come down, not only sperm antibodies. As a result, you will often experience pain, and even affects the bone marrow that causes slow blood rejuvenation, lead to osteoporosis, the risk of diabetes, and others.
A person who has excessive sperm antibodies will also be difficult to have children with the test-tube baby. Because the antibodies will not only reject the sperm, but also rejecting the fetus result of fertilization of the sperm.
Thus the explanation that can be delivered, may help. thanks
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